Iron deficiency anemia is highly prevalent among pregnant women, particularly in developing countries where rates range from 35-75%, and poses significant health risks, including the potential for congestive heart failure and increased maternal and fetal mortality in severe cases.

A retrospective study reviewed the effectiveness of various iron supplements administered across the trimesters of pregnancy, focusing on their impact on preventing iron deficiency anemia. The study involved 199 participants at a Greek university hospital, with treatments ranging from iron protein acetyl aspartilate plus calcium folinate pentahydrate to more common supplements like ferrous sulfate. Initial results indicated improvements in hemoglobin and hematocrit levels, with ongoing assessments into the postpartum period. The comprehensive evaluation aims to better understand the optimal iron supplementation strategy during pregnancy to mitigate the adverse effects of anemia and enhance maternal and fetal health outcomes.

Reference: Constantinos B, Bothou A, Oikonomou E, et al. A Retrospective Study of Various Iron Preparations Oral Administration in Pregnant Women with Iron Deficiency Anemia. Mater Sociomed. 2023;35(2):157-164. doi: 10.5455/msm.2023.35.157-164. PMID: 37701349; PMCID: PMC10495134.